Lumacaftor 936727-05-8

Lumacaftor

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Supplier Details

Nanjing Xinbell Pharmaceutical Technology Co., Ltd. [Audited]

  • Member Levels: Diamond memberDiamond member
  • Business Type: Other
  • Country: China
  • Tel: 86-25-83240338
  • Address: Room 1415, Wanda Plaza, No. 133 Fuyuan Street, Jianye District, Nanjing, Jiangsu 210017, China
  • Jian Jiang:
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3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-benzoic acidQuick Details

  • Classification:Pharmaceutical
  • Cas NO.:936727-05-8
  • Molecular Formula:C24H18F2N2O5
  • Boiling Point:653.013°C at 760 mmHg
  • Refractive index:1.67
  • Flash Point:348.73°C

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Detailed Description

Lumacaftor (VX-809) is a pharmaceutical drug that acts as a chaperone during protein folding and increases the number of CFTR proteins that are trafficked to the cell surface. It is available in a single pill with ivacaftor; the combination, lumacaftor/ivacaftor (brand name Orkambi), is used to treat people with cystic fibrosis who have the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), the defective protein that causes the disease.

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