Formamida

La formamida es un líquido incoloro, inodoro e higroscópico a temperatura ambiente, con un punto de ebullición elevado (210 °C) y baja volatilidad. Es un compuesto orgánico polar funcionalizado con grupo amida, clasificado como una amida primaria, y se utiliza ampliamente como disolvente versátil e intermediario sintético. Su elevada capacidad de formación de enlaces de hidrógeno y su estabilidad térmica la convierten en un producto valioso para la síntesis de productos farmacéuticos, agroquímicos y compuestos heterocíclicos, incluidos derivados de purina y pirimidina. La formamida actúa como precursor clave en la producción de ácido fórmico, cianuro de hidrógeno y diversos colorantes, además de emplearse también como disolvente en el procesamiento de polímeros, la fabricación electrónica y los recubrimientos especiales.

It can be used as the raw material for synthesizing imidazole, pyrimidine, 1, 3, 5-triazine, caffeine as well as the solvents for making spinning of acrylonitrile copolymer and plastic anti-static coating, etc. Formamide has active reactive and special dissolving capability. It can be used as the raw material for organic synthesis, paper processing agents, softening agent of fiber industry and animal glue as well as being used as the analytical reagent for measuring the amino acid content of rice. In the field of organic synthesis, it has most application in medicine as well as a lot of applications in other fields such as pesticides, dyes, pigments, fragrances and additives. It is also a kind of excellent organic solvent and is mainly applied to the spinning of acrylonitrile copolymers and ion exchange resins and plastics antistatic coating or conductive coating. In addition, it can also be used for separating chlorosilane and purifying grease. Formamide can have various kinds of reactions, in addition to have its three hydrogen atoms participate in the reaction, can also be subject to dehydration, CO removal, the introduction of an amino group, an acyl group and cyclization reaction. Take cyclization as an example, diethyl malonate can have cyclization reaction with formamide to generate the intermediate of vitamin B4, the 4, 6-dihydroxypyrimidine. O-aminobenzoic acid can have cyclization reaction with formamide to generate the quinazolinone-4 which is the intermediate for the synthesis of antiarrhythmic drug phenantrolihne. 3--amino-4-ethoxycarbonyl-pyrazole can have cyclization reaction with formamide to generate the inhibitor of the xanthine oxidase, allopurinol. EDTA can have cyclization reaction with formamide to give anti-cancer drugs ethylenediamine. Methyl ethyl methoxymalonate can have cyclization reaction with formamide to generate the intermediate of sulfonamide drug, 5-methoxy-4, 6-dihydroxy pyrimidine disodium.It can be used as analytical reagents, solvents and softening agents as well as being used in organic synthesis.It can be applied to medicine and pesticide industry.

Este producto químico está incluido en Químicos Finos. Consulte más información sobre qué es Formamida y la información SDS de Formamida.

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