D-Valine

D-Valine est un solide cristallin blanc, inodore et peu volatil ; son point de fusion est d’environ 295–297 °C (avec décomposition). Il constitue l’énonémer dextrogyre de l’acide α-aminé valine, qui se trouve naturellement, et est classé comme composé organique chiral et intermédiaire amino-acidique spécialisé. Sur le plan industriel, le D-Valine sert principalement de bloc de construction dans la synthèse de produits pharmaceutiques — notamment des antibiotiques β-lactames (par exemple, certaines céphalosporines) et des inhibiteurs de protéases — ainsi que de synthon chiral dans la catalyse asymétrique et le développement de médicaments peptidiques. Ses domaines d’application principaux sont les produits pharmaceutiques et la synthèse de produits chimiques fins, où son intégrité stéréochimique permet un contrôle précis de la configuration moléculaire des principes actifs pharmaceutiques.

1. D-valine can be used for the synthesis of newly efficient pesticide: pyrethroids permethrin and chlorofluorocarbons amyl because of its own biochemical characteristics. The produced valine insecticide permethrin is a broad-spectrum and promising insecticide acaricide which can have effects of touch-killing and stomach poisoning through inhibiting the activity of related enzyme systems of insects. In this way, it can be used for effectively controlling of major pests including Lepidoptera and Diptera in corps such as cotton, fruit trees, and vegetables. D-valine is also widely used in biomedical research. For example, it can be used to inhibit the growth of fibroblasts, and be applied to the studies on its influence on the morphology and function of pulmonary artery endothelial cells. D-valine are also important raw materials as chiral drugs for example it may be used for the synthesis of antineoplastic drugs, anti-diabetes and its complications drugs. With the expansion of the applications fields as well as market demanding of D-valine, the preparation of D-valine will become a hot research field on amino acid.2. D-Valine is an important organic chiral source which is mainly used in fields such as chiral pharmaceuticals, chiral additive, and chiral auxiliary and other areas. It can also be used as the chiral source of chiral synthesis in the pharmaceutical industry. As an optically active organic acid, it plays an irreplaceable role in the asymmetric synthesis of certain chiral compounds. It is currently mainly used for the production of new broad-spectrum antibiotic, D-valinol, and valine protective agent during the process of peptide synthesis.3. D-valine is the intermediates for fluvalinate. 4. It is used as a pharmaceutical raw materials and pharmaceutical intermediates, and can also be used for synthetic sweeteners Alatan.5. It can also be used for biochemical research.

Ce produit chimique est inclus dans Produits chimiques fins. Consultez davantage d’informations sur ce qu'est D-Valine ainsi que les informations SDS de D-Valine.

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