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D-Valine

  • 200000CNY/TON Updated: 2026-08-07
  • Price change (DoD): 0
    Average price (3M):200000 CNY/TON
    Price Level(1Y):High
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D-Valine Prices Trends in China

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D-Valine Prices sources

Reg Spec 2026/08/03 2026/08/05 2026/08/07 ChangeUnit Comparison

D-Valine Market share- How big is the D-Valine market?

China and India are the leading exporters of D-Valine, accounting for the majority of global shipments, while the United States, Germany, and Japan represent the largest importers. D-Valine prices have remained relatively stable amid steady demand from pharmaceutical and agrochemical manufacturers. Export volumes from China increased modestly in 2023–2024, while Indian exports showed accelerated growth, reflecting expanded API intermediate production capacity.

D-Valine Market Analysis

D-Valine Market Dynamics Report (Recent Commodity Market Intelligence)

I. Price Trends
- Latest Quotation: As of July 27, 2026, the spot price for domestically produced valine (98.5% purity) stands at RMB 10.6 per kilogram, unchanged from the previous day.
- Recent Volatility: No price change occurred over the past week (July 21–27), remaining stable at RMB 10.6/kg; over the past month (June 29–July 27), the price declined by RMB 0.2/kg, representing a cumulative decrease of 1.85%.
- Historical Comparison: On July 14, the price briefly dropped to RMB 10.6/kg—down RMB 0.15/kg (a 1.40% decline) from July 10—but subsequently stabilized over the following week.

II. Supply and Demand
- Supply Side:
- Major domestic suppliers include Hubei Julongtang Pharmaceutical & Chemical Co., Ltd. and Shanghai Kangtuo Chemical Co., Ltd., with production capacity concentrated in Hubei and Shanghai provinces.
- Fermentation is the predominant manufacturing process; a minority of producers employ chemical synthesis. However, due to tightening environmental regulations, the share of fermentation-based production continues to rise.
- No new production capacity has recently come online; overall supply remains stable.
- Demand Side:
- Pharmaceutical Sector: As a chiral drug intermediate, demand is driven by production of novel antibiotics and flumethrin, among others; however, short-term growth remains modest.
- Food Industry: Used as a nutritional fortifier, demand is gradually increasing alongside rising health-conscious food consumption, though its share in total demand remains relatively low.
- Feed Industry: Demand fluctuates with livestock cycles; recent rebound in hog prices may boost demand for feed additives, albeit with only moderate overall growth.

III. Costs and Profitability
- Raw Material Costs: L-Valine—the primary raw material—is subject to price fluctuations in agricultural commodities such as corn and soybeans. Corn prices have recently stabilized, alleviating cost pressure.
- Production Costs: Fermentation-based production costs range approximately RMB 8–9/kg; chemically synthesized valine incurs slightly higher costs (RMB 9–10/kg). At the current market price of RMB 10.6/kg, profit margins for manufacturers remain narrow.
- Profit Levels: Industry-average gross margin stands at 10%–15%. While some enterprises have enhanced profitability via technological optimization, overall margins remain constrained by pricing pressures.

IV. Competitive Landscape
- Domestic Players: Hubei Julongtang and Shanghai Kangtuo collectively command over 60% of market share, dominating the industry; smaller enterprises primarily serve regional markets.
- International Players: Multinational corporations such as Ajinomoto and CJ leverage technological advantages to target high-end segments, whereas domestic firms maintain dominance in mid-to-lower-tier markets thanks to cost competitiveness.
- Pricing Competition: No aggressive price wars have emerged recently; instead, companies pursue differentiation through product quality enhancement and service improvements.

V. Regulatory and Environmental Factors
- Environmental Regulations: Rising wastewater treatment costs associated with chemical synthesis have forced some producers to suspend operations or transition to fermentation processes; fermentation now accounts for over 70% of total production capacity.
- Industry Standards: The State Administration issued the “Regulatory Conditions for Amino Acid Industry,” raising entry thresholds and intensifying consolidation pressure on small- and medium-sized enterprises.

Analysis and Assessment
1. Short-Term Price Stability: Current pricing has approached the marginal cost floor, leaving minimal room for further reductions. Coupled with absence of major negative demand drivers, prices are expected to hold steady at RMB 10.6/kg in the near term.
2. Easing Supply-Demand Imbalance: With no new capacity additions on the supply side and modest demand recovery supported by livestock cycles, the supply-demand gap is narrowing, resulting in reduced price volatility.
3. Strengthening Cost Support: Stabilized corn prices—combined with rising environmental compliance costs—provide upward support to market pricing.

Outlook
1. Price Forecast:
- Short Term (1–3 months): Prices are projected to oscillate within a narrow band of RMB 10.5–10.8/kg, with volatility below 5%.
- Medium Term (6–12 months): Should livestock-related demand exceed expectations, prices could rise modestly to RMB 11.0–11.2/kg; conversely, a decline in raw material costs could push prices down to RMB 10.2–10.5/kg.
2. Market Opportunities:
- High-End Segment: Growing demand for chiral pharmaceutical intermediates presents an opportunity for enterprises to invest in R&D, enhance product purity (e.g., ≥99.5%), and capture premium-market share.
- Export Expansion: Rising demand in Southeast Asia and India offers potential for overseas channel development and increased export penetration.
3. Risk Alerts:
- Raw Material Price Volatility: Corn and soybean prices remain vulnerable to climatic conditions and trade policy shifts, potentially triggering significant cost fluctuations.
- Tightening Environmental Regulations: Further tightening of wastewater discharge standards could increase production costs by 10%–15%.

About D-Valine

D-Valine is a white, crystalline solid with no characteristic odor and low volatility; it has a melting point of approximately 295–297 °C (with decomposition). It is the dextrorotatory enantiomer of the naturally occurring α-amino acid valine and is classified as a chiral organic chemical and specialty amino acid intermediate. Industrially, D-valine serves primarily as a building block in the synthesis of pharmaceuticals—particularly β-lactam antibiotics (e.g., certain cephalosporins) and protease inhibitors—and as a chiral synthon in asymmetric catalysis and peptide-based drug development. Its principal application areas are pharmaceuticals and fine chemical synthesis, where its stereochemical integrity enables precise control over molecular configuration in active pharmaceutical ingredients.

1. D-valine can be used for the synthesis of newly efficient pesticide: pyrethroids permethrin and chlorofluorocarbons amyl because of its own biochemical characteristics. The produced valine insecticide permethrin is a broad-spectrum and promising insecticide acaricide which can have effects of touch-killing and stomach poisoning through inhibiting the activity of related enzyme systems of insects. In this way, it can be used for effectively controlling of major pests including Lepidoptera and Diptera in corps such as cotton, fruit trees, and vegetables. D-valine is also widely used in biomedical research. For example, it can be used to inhibit the growth of fibroblasts, and be applied to the studies on its influence on the morphology and function of pulmonary artery endothelial cells. D-valine are also important raw materials as chiral drugs for example it may be used for the synthesis of antineoplastic drugs, anti-diabetes and its complications drugs. With the expansion of the applications fields as well as market demanding of D-valine, the preparation of D-valine will become a hot research field on amino acid.2. D-Valine is an important organic chiral source which is mainly used in fields such as chiral pharmaceuticals, chiral additive, and chiral auxiliary and other areas. It can also be used as the chiral source of chiral synthesis in the pharmaceutical industry. As an optically active organic acid, it plays an irreplaceable role in the asymmetric synthesis of certain chiral compounds. It is currently mainly used for the production of new broad-spectrum antibiotic, D-valinol, and valine protective agent during the process of peptide synthesis.3. D-valine is the intermediates for fluvalinate. 4. It is used as a pharmaceutical raw materials and pharmaceutical intermediates, and can also be used for synthetic sweeteners Alatan.5. It can also be used for biochemical research.

This chemical is included in Fine Chemicals. See more about what is D-Valine and D-Valine SDS information.

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