China and India are the leading exporters of 4-Cyanopyridine (CAS 100-48-1), accounting for the majority of global shipments, while the United States, Germany, and South Korea represent the largest importing markets. Recent trade data shows relative stability in export volumes from Asia, though fluctuations in 4-Cyanopyridine prices have accompanied shifts in regional procurement patterns, particularly among European pharmaceutical intermediates buyers.
Market Intelligence on 4-Cyanopyridine
I. Price Trends
1. Domestic Market
- Over the past week, mainstream prices for 4-cyanopyridine in the East China region have fluctuated between 125,000 and 132,000 RMB/ton, representing a month-on-month increase of approximately 3.8%, primarily driven by rising raw material costs and support from essential downstream procurement.
- Prices in the South China region are slightly higher, ranging from 128,000 to 135,000 RMB/ton, due to regional supply tightness and increased logistics costs.
2. International Market
- The CFR price in the Indian market remains stable at USD 1.85–1.92/kg, with no significant fluctuations recently, influenced by the transmission of domestic export prices.
- In the European market, prices are maintained at EUR 1.95–2.05/kg due to persistently high energy costs, representing a premium of approximately 15% over domestic prices.
II. Supply and Demand Dynamics
1. Supply Side
- The operating rate of major domestic production enterprises is approximately 75%, remaining flat month-on-month. However, temporary production cuts by some manufacturers due to environmental inspections have led to regional supply tightness.
- Import volumes have decreased by 12% month-on-month, as international suppliers prioritize orders from the US and Europe, reducing export quotas to China.
2. Demand Side
- Demand for downstream pesticide intermediates has increased by 8%, driven by the early start of spring planting stockpiling, which has boosted raw material procurement.
- Demand in the pharmaceutical intermediate sector remains stable; however, affected by centralized procurement policies, some enterprises are pressing for lower prices, which has suppressed price increases.
III. Costs and Profits
1. Raw Material Costs
- Pyridine prices have risen by 10% year-on-year, increasing the production cost of 4-cyanopyridine by approximately 800 RMB/ton.
- Sodium cyanide prices remain at high levels, further compressing production profits. The current average gross profit margin for the industry is approximately 12%, down by 3 percentage points compared to the same period last year.
2. Profit Margins
- Leading enterprises, benefiting from economies of scale and advantages in raw material procurement, maintain gross profit margins of 15%–18%, while profits for small and medium-sized enterprises have been compressed to below 8%.
IV. Inventory and Logistics
1. Inventory Levels
- Total domestic social inventory is approximately 1,200 tons, down by 15% month-on-month, representing a three-year low, primarily due to reduced supply and early stockpiling by downstream users.
- Port inventory is approximately 300 tons, down by 20% year-on-year, driven by decreased import volumes and increased export orders.
2. Logistics Impact
- Snow and rain weather in the East China region have caused transportation delays, leading to localized spot shortages and exacerbating price volatility.
- Export shipping costs have increased by 10%, prompting some enterprises to delay shipments to mitigate cost pressures.
V. Policy and Industry Trends
1. Environmental Policies
- Special rectification campaigns for chemical industrial parks are underway in Shandong and Jiangsu, resulting in production halts and maintenance for some enterprises, with an estimated impact of approximately 200 tons on monthly output.
2. Industry News
- A leading enterprise plans to add 5,000 tons/year of production capacity, with an expected commissioning date in 2025, which may alleviate supply tightness in the long term.
VI. Analysis and Forecast
1. Short Term (1–2 Weeks)
- Prices are expected to remain high with volatility, in the range of 128,000–135,000 RMB/ton, supported by tight supply and costs.
- Attention should be paid to the continued impact of snow and rain weather on logistics and changes in downstream procurement pace.
2. Medium Term (1–3 Months)
- As spring planting stockpiling concludes, demand may slightly decline, potentially causing prices to adjust to 122,000–128,000 RMB/ton.
- If raw material pyridine prices soften, cost pressures may ease, allowing for a slight recovery in profit margins.
3. Long Term (3–6 Months)
- Prior to the introduction of new production capacity, the market supply-demand structure will remain tight, and the price center may shift upward to 130,000–140,000 RMB/ton.
- Caution is advised regarding the risk of phased supply disruptions caused by stricter environmental policies.
4-Cyanopyridine is a white to off-white crystalline solid at room temperature, with a faint, characteristic odor and moderate volatility; it melts at approximately 65–67 °C and boils at around 265 °C. It is an aromatic heterocyclic compound classified as a pyridine derivative and widely employed as a versatile synthetic intermediate. Its primary industrial use is in the production of pharmaceuticals—particularly nicotinamide analogues and kinase inhibitors—and agrochemicals, including herbicides and plant growth regulators. It also serves as a building block for specialty dyes, corrosion inhibitors, and functional materials in electronic applications.
beige solid
This chemical is included in Fine Chemicals. See more about what is 4-Cyanopyridine and 4-Cyanopyridine SDS information.
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