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Germany and the United States are the leading exporters of Tosylmethyl isocyanide (CAS 36635-61-7), accounting for the majority of global shipments, while pharmaceutical and fine chemical–focused importers—including Japan, South Korea, and Switzerland—represent the most consistent demand centers. Trade volumes have remained relatively stable over the past three years, with modest upward pressure on Tosylmethyl isocyanide prices reflecting tightening supply from specialized European producers.
Tosylmethyl isocyanide (CAS 36635-61-7) is a white to off-white crystalline solid at room temperature, typically odorless or with a mild, characteristic isocyanide scent; it exhibits moderate volatility and decomposes before boiling, with a reported melting point near 70–72 °C. It is classified as an aromatic organic compound and functions primarily as a specialty synthetic intermediate containing both a tosyl (p-toluenesulfonyl) group and a reactive isocyanide functionality. Its principal industrial use is in multicomponent reactions—particularly the Passerini and Ugi reactions—for constructing complex nitrogen-containing scaffolds. It is employed in research and production settings for synthesizing pharmaceutical intermediates, agrochemical actives, and functionalized heterocycles, with applications concentrated in fine chemical and active pharmaceutical ingredient (API) development.
Reagent for use in the preparation of biologically active pyrroles and imidazoles.1,2
Pale yellow to light brown crystalline powder
This chemical is included in Fine Chemicals. See more about what is Tosylmethyl Isocyanide and Tosylmethyl Isocyanide SDS information.
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