China and the United States are the leading exporters of Nonafluorobutanesulfonyl fluoride (CAS 375-72-4), accounting for the majority of global shipments, while Japan, South Korea, and Germany represent the largest importers, driven by demand from specialty chemical and pharmaceutical manufacturing sectors. Recent trade data shows stable export volumes from China alongside modest growth in U.S. exports, while Nonafluorobutanesulfonyl fluoride prices have remained relatively firm amid tightening supply constraints and sustained end-user demand.
Nonafluorobutanesulfonyl fluoride is a colorless to pale yellow, volatile liquid with a pungent odor and low melting point (–15 °C) and boiling point (~70–75 °C at reduced pressure). It is a perfluoroalkyl sulfonyl fluoride, classified as a specialty fluorinated organic intermediate. Primarily employed in synthetic chemistry, it serves as a key reagent for introducing the nonafluorobutanesulfonyl (Nf) group—valued for its strong electron-withdrawing character and steric bulk—to nitrogen, oxygen, sulfur, and carbon nucleophiles. Its principal applications are in the preparation of Nf-protected amines, alcohols, and thiols for use in pharmaceutical and agrochemical synthesis, as well as in the development of advanced catalysts, ionic liquids, and functional polymers.
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