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China and India are the leading exporters of Isobutyl chloroformate (CAS 543-27-1), collectively accounting for over 60% of global export value in 2023–2024, while the United States, Germany, and South Korea represent the largest importers. Import volumes into the U.S. and EU have remained stable since 2022, with modest upward pressure on Isobutyl chloroformate prices reflecting tightening supply from key Asian producers.
Isobutyl chloroformate is a colorless to pale yellow, fuming liquid with a pungent, acrid odor and high volatility; it has a boiling point of approximately 135–137 °C and decomposes upon prolonged exposure to moisture. It is classified as a reactive acylating agent and organic chloroformate derivative. Primarily employed as a coupling reagent and protecting-group reagent in synthetic organic chemistry, it facilitates the formation of carbamates, carbonates, and esters under mild conditions. Its principal applications are in the pharmaceutical industry for peptide synthesis and active pharmaceutical ingredient (API) manufacturing, and in agrochemical synthesis for herbicide and insecticide intermediates.
Peptide reagent.
clear liquid
This chemical is included in Fine Chemicals. See more about what is Isobutyl Chloroformate and Isobutyl Chloroformate SDS information.
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