3-Aminophenol

3-Aminophenol is a white to pale pink crystalline solid with a faint, characteristic odor; it has a melting point of approximately 122–124 °C and is moderately soluble in water and organic solvents. It is an aromatic organic compound classified as a substituted phenol and primary aromatic amine. Primarily used as a chemical intermediate, it serves in the synthesis of dyes (especially azo and sulfur dyes), pharmaceuticals (e.g., analgesics and antipyretics), and photographic developers. Its applications are concentrated in the dyes and pigments, pharmaceuticals, and imaging chemicals sectors.

m-Aminophenol (MAP) is an important starting material for dyes, including a variety of leuco (or latent) dyes used in imaging technology, optical bleaches and fluorescent agents, drugs, agricultural chemicals; and high-performance polymers. Although the synthesis of m-aminophenol(s) by the reaction of resorcinol with ammonia or (di)alkylarnines has been known for about 100 years,the preferred manufacturing process had been for many years a route involving the sulfonation of nitrobenzene to m-nitrobenzenesulfonic acid, the reduction of the nitro group to give m-aminobenzenesulfonic acid, followed by the caustic fusion of sodium m-aminobenzenesulfonate to yield sodium m-aminophenolate. The m-aminophenol was isolated/purified by neutralization, filtration, and recrystallization; the overall yield of m-aminophenol from nitrobenzene was estimated by SRI International to be 58%. (Doubtless, process improvements were made by the producers using this process.) The nitrobenzene/sulfonationlreductionlcaustic fusion route is still being used commercially, notably by ACNA in Italy, the largest producer of MAP, as well as a few smaller manufacturers. Sumitomo Chemical Co. used this process as well into the early 1980s and had licensed their knowhow to Hindustani Organic Chemicals, Ltd. of India which started up a plant on this basis with a capacity for MAP of 1.5 mill. lb /yr in 1970.The output of the Indian plant was said to be devoted to making sodium p-aminosalycilate (PAS), a tuberculostatic agent.
Light grey crystal powder

This chemical is included in Fine Chemicals - Cosmetics Raw Materials. See more about what is 3-Aminophenol and 3-Aminophenol SDS information.

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