China and India are the leading exporters of 4'-Hydroxypropiophenone (CAS 70-70-2), accounting for the majority of global supply, while the United States, Germany, and South Korea represent the largest importers. These importing nations consistently absorb significant volumes, reflecting steady industrial demand—particularly in pharmaceutical and agrochemical intermediates. Trade flows have remained relatively stable over the past three years, with modest growth in imports by Southeast Asian countries coinciding with upward pressure on 4'-Hydroxypropiophenone prices amid tightening regional supply chains.
# 4-Hydroxypropiophenone Market Dynamics Intelligence
## I. Basic Product Information
| Item | Content |
|------|------|
| Chemical Name | 4-Hydroxypropiophenone |
| CAS No. | 70-69-9 |
| Molecular Formula | C9H10O2 |
| Main Uses | Pharmaceutical intermediate (e.g., synthesis of Trihexyphenidyl Hydrochloride), fragrance raw material, organic synthesis intermediate |
| Main Production Areas | Shandong, Jiangsu, Hebei, etc. |
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## II. Market Dynamics Intelligence for the Last Month
### 2.1 Supply-Side Dynamics
- **Raw Materials**: Upstream raw materials such as phenol and propionyl chloride/propionic acid have maintained a weak and fluctuating trend in the past month. Affected by sluggish downstream demand, phenol prices have slightly declined, weakening the cost support for 4-hydroxypropiophenone.
- **Production**: The operating rate of major domestic producers remains at a moderate level (approximately 60%-70%). Some small and medium-sized enterprises have experienced phased production cuts due to environmental inspections and compressed profit margins. Some units in Shandong are operating normally, while individual enterprises in Jiangsu have maintenance plans.
- **Inventory**: Overall social and corporate inventories are at a medium-to-high level. Downstream procurement pace is slow, resulting in a slow inventory reduction rate.
### 2.2 Demand-Side Dynamics
- **Pharmaceutical Intermediate Demand**: Demand for downstream pharmaceutical intermediates such as Trihexyphenidyl Hydrochloride is stable, with no significant volume increase. Terminal pharmaceutical companies are procuring based on essential needs, with weak inventory replenishment willingness.
- **Fragrance and Other Demand**: Fragrance industry demand is seasonally weak. Export order volumes have slightly decreased compared to the previous month, with fewer inquiries from Southeast Asian and European markets.
- **Overall Demand**: Overall downstream demand shows a mildly weak trend, and market trading activity is average.
### 2.3 Price Dynamics
- **Domestic Market**: In the past month, the mainstream quote range for 4-hydroxypropiophenone was approximately **18,000-22,000 RMB/ton**, a slight decrease of about 200-500 RMB/ton compared to the previous month. Actual transaction prices were at the lower end of the range.
- **Export Market**: FOB quotes have slightly softened. Affected by RMB exchange rate fluctuations and weak international demand, export prices are under pressure.
- **Price Trend**: The overall trend is a narrow-range decline, with the market lacking clear positive drivers.
### 2.4 Policy and Logistics
- Environmental inspections continue to be enforced. Some chemical enterprises in certain regions face production restriction pressures, but the direct impact on this product is limited.
- Logistics transportation is normal, with no obvious bottlenecks.
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## III. Analysis and Judgment
| Dimension | Judgment |
|------|------|
| **Supply-Demand Structure** | The supply-exceeds-demand structure has not changed in the short term. Supply-side capacity is ample, while the demand side lacks incremental drivers. |
| **Cost Support** | Upstream raw material prices, such as phenol, are weak. Cost support is shifting downward, compressing production profits. |
| **Market Sentiment** | A strong wait-and-see sentiment prevails. Traders and downstream buyers are mainly focused on price suppression, and market confidence is insufficient. |
| **Competitive Landscape** | There are many domestic producers with obvious homogeneous competition, leading to sustained price war pressure. |
| **Short-Term Drivers** | No major sudden events or policy benefits. The market is driven primarily by weak fundamentals. |
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## IV. Forecast
| Time Period | Forecast |
|----------|------|
| **Next 2 Weeks** | Prices are expected to fluctuate in the **17,500-21,500 RMB/ton** range. Downward pressure remains. If raw material prices continue to weaken, prices may test lower levels. |
| **Next 1 Month** | Prices are expected to be **stable but weak** in tone. If downstream pharmaceutical orders are released in a concentrated manner or if phenol prices rebound, there may be a phased slight rebound (1,000-2,000 RMB/ton), but the probability of a significant increase is low. |
| **Medium to Long Term (1-3 Months)** | Key factors to monitor: ① Downstream new drug approvals and volume release; ② The intensity of environmental policies in eliminating small and medium-sized production capacity; ③ The pace of export market recovery. If there is no significant improvement in demand, the price center may shift further downward. |
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## V. Risk Warnings
1. **Raw Material Price Volatility Risk**: Significant fluctuations in raw materials such as phenol and propionic acid will directly transmit to the cost side.
2. **Environmental Policy Risk**: If environmental production restrictions are tightened in key production areas, supply may be disrupted in the short term, causing price pulses.
3. **Demand Underperformance Risk**: If terminal pharmaceutical demand remains sluggish, market prices will be further suppressed.
4. **International Trade Risk**: Export markets face uncertainties due to geopolitical factors and tariff policies.
4′-Hydroxypropiophenone is a white to off-white crystalline solid at room temperature, with a mild aromatic odor and a melting point of approximately 75–77 °C. It is an aromatic ketone and phenolic compound, classified as a fine organic chemical intermediate. Industrially, it serves primarily as a key building block in the synthesis of pharmaceuticals—including nonsteroidal anti-inflammatory drugs (NSAIDs) such as ketoprofen—and agrochemicals like certain herbicides and plant growth regulators. Its applications are concentrated in pharmaceutical and agrochemical manufacturing, where it functions as a precursor in multi-step syntheses requiring both aryl ketone and phenolic functionalities.
gonadotropic hormone inhibitor
white powder
This chemical is included in Fine Chemicals. See more about what is 4'-Hydroxypropiophenone and 4'-Hydroxypropiophenone SDS information.
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