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China and India are the leading global exporters of Melatonin (CAS 73-31-4), accounting for the majority of international supply, while the United States, Germany, and Japan represent the largest importers by value. Melatonin prices have remained relatively stable amid consistent demand from pharmaceutical and nutraceutical markets. Exports from China have expanded steadily since 2022, while U.S. imports have grown at an annualized rate of ~4% over the past three years, reflecting sustained regulatory acceptance and formulation demand.
Melatonin (CAS 73-31-4) is a white to off-white crystalline powder at room temperature, odorless, with a melting point of approximately 116–118 °C and low volatility. It is a naturally occurring indoleamine derivative—specifically, an N-acetyl-5-methoxytryptamine—and classified as a heterocyclic organic compound. Industrially, melatonin is primarily manufactured as an active pharmaceutical ingredient (API) for use in dietary supplements and prescription medications targeting sleep disorders. Its principal application area is human health products, particularly in the pharmaceutical and nutraceutical sectors; it is not used as a chemical intermediate in agrochemicals, dyes, polymers, or other industrial material syntheses.
Melatonin is a slightly off-white, odourless crystalline powder. It is very slightly soluble in water and in dilute hydrochloric acid.
This chemical is included in Fine Chemicals - Pharmaceutical Intermediates & APIs. See more about what is Melatonin and Melatonin SDS information.
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