Recent Commodity Market Dynamics Intelligence
1. **Price Trends**
- Over the past week, the mainstream transaction price of ethyl p-aminobenzoate in the domestic market fluctuated within the range of 12,000 - 12,500 RMB/ton, representing a slight increase of 2% - 3% compared to the previous week.
- In the international market, prices in Asia were quoted at 1,700 - 1,800 USD/ton (CFR China), remaining largely flat compared to the previous week; prices in Europe ranged from 1,850 - 1,950 EUR/ton, showing a slight increase of about 1%.
2. **Supply Situation**
- The operating rates of major domestic producers remained between 75% and 80%. Although some companies experienced temporary production cuts due to equipment maintenance, the overall supply volume did not fluctuate significantly.
- Regarding imports, the volume of recently arrived cargo remained stable, primarily sourced from India and South Korea, with import volumes showing little change compared to the same period last month.
3. **Demand Situation**
- Demand from downstream industries such as pharmaceuticals and dyes remained steady, with purchases driven by immediate needs. In the pharmaceutical sector, there is stable demand for ethyl p-aminobenzoate in the production of certain anti-allergy drugs. In the dye industry, it is used as an intermediate for synthesizing specific dyes, with no significant growth in demand.
- The export market performance was satisfactory, with small volumes of orders shipped to Southeast Asia in recent weeks, marking a roughly 5% increase in export volume compared to the previous week.
4. **Cost Aspects**
- The price of the main raw material, p-aminobenzoic acid, remained stable recently at 8,000 - 8,500 RMB/ton, providing certain cost support for ethyl p-aminobenzoate.
- Energy costs, including coal and natural gas, showed minimal fluctuation, having a limited direct impact on production costs.
Analysis and Judgment
1. **Reasons for Price Fluctuations**
- The slight increase in domestic prices was mainly influenced by production cuts at some enterprises, leading to a local tightening of market supply and driving prices up slightly.
- The price increase in the European market was primarily due to a slight increase in local demand and supply constraints at some production facilities; the flat prices in the Asian market reflect a relatively balanced supply and demand.
2. **Supply and Demand Relationship**
- The current market supply and demand are basically balanced. Although there are local production cuts on the supply side, the overall output still meets demand, and imported cargo supplements are timely.
- On the demand side, performance remains steady, with downstream industries purchasing according to immediate needs. The slight growth in the export market has exerted some pulling effect on demand, but the overall intensity is limited.
3. **Cost Support**
- The stable price of the raw material p-aminobenzoic acid provides cost support for ethyl p-aminobenzoate, limiting the downside risk for prices.
Forecast
1. **Short-term (1 - 2 weeks)**
- Prices are expected to fluctuate within the current range. Domestic prices will remain between 12,000 - 12,500 RMB/ton, Asian international quotes at 1,700 - 1,800 USD/ton (CFR China), and European prices at 1,850 - 1,950 EUR/ton.
- On the supply side, as maintenance periods conclude and enterprises resume production, supply volumes will increase slightly; demand remains unchanged, with steady purchasing patterns.
2. **Medium-term (1 - 2 months)**
- If there is no significant growth in demand from downstream industries such as pharmaceuticals and dyes, prices may experience a slight correction, with domestic prices potentially dropping to 11,500 - 12,000 RMB/ton.
- Supply will be ample as capacity is released; if the export market maintains steady growth, it will provide some support for prices, curbing the extent of the decline.
3. **Long-term (3 - 6 months)**
- Price trends will depend on the growth of downstream demand and fluctuations in raw material prices. If downstream industry demand remains sluggish, prices may continue to decline; if demand shows significant growth or raw material prices rise substantially, prices will follow suit.
Benzocaine is a local anaesthetic of the ester type with a poor solubility in water. The drug benzocaine is normally used as a topical pain reliever or as a common ingredient in cough drops. Benzocaine is used in multiple forms including lotion, gel, liquid, lozenges, and sprays. When Benzocaine is applied in any form it temporarily numbs or blocks the nerve endings, which leads to a decreases in the amount of pain. It is used in cattle, sheep, swine and horses for local and prolonged low epidural anaesthesia. Standard therapeutic doses of benzocaine ranged from 150 to 750 mg per animal. Benzocaine is also currently used as surface anaesthetic as ointments (0.5% benzocaine) for wounds and ulcerated surfaces in horses, cattle and sheep applied twice a day until healing.A commonly used topical pain reliever. Main active ingredient in anesthetic ointments.Anesthetic;Na+ channel blockerBenzocaine acts on the central nervous system, cardiovascular system, neuromuscular junctions and ganglion synapse. Its mechanism of action is to prevent the generation and conduction of the nerve impulse. Local anaesthetics block conduction by decreasing or preventing the large transient increase in the permeability of excitable membranes to Na+ that is produced by a slight depolarisation. This action of local anaesthetics is due to their direct interaction with voltage-sensitive Na+ channels. Benzocaine is mainly hydroxylated in the metabolite para-aminobenzoic acid (PABA) that inhibits the action of sulphonamides.Benzocaine is distributed in the body, crosses the placenta and is metabolised in the liver and in the plasma by non-specific cholinesterases. Benzocaine and its main metabolite (para-aminobenzoic acid) are excreted into urine.Benzocaine appears as a moderately toxic compound after single administration. The acute intraperitoneal LD50 value was 216 mg/kg bw in mice. Benzocaine may induce methemoglobinemia in several species such as sheep, cats and dogs.
white odourless crystals
This chemical is included in Fine Chemicals - Pharmaceutical Intermediates & APIs. See more about what is Benzocaine and Benzocaine SDS information.
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