Germany, the United States, and China are the leading exporters of chloral hydrate, collectively accounting for over 60% of global exports in recent years; major importers include India, South Korea, and Brazil, primarily for pharmaceutical intermediate use. Import volumes to India and South Korea have risen steadily since 2022, coinciding with moderate upward pressure on chloral hydrate prices amid tightening supply-side regulation and consolidation among EU-based producers.
Chloral hydrate is a colorless, crystalline solid with a pungent, chloroform-like odor and moderate volatility; it melts at approximately 57 °C and decomposes before boiling. It is an organochlorine compound classified as a geminal diol and serves primarily as a chemical intermediate. Its principal industrial use is in the synthesis of chloral derivatives, notably DDT (historically) and the pharmaceutical agent trichloroacetic acid. It is employed in the production of agrochemicals and certain pharmaceuticals, though its direct applications in modern manufacturing are limited and highly specialized.
Trichloroacetaldehyde Hydrate is a useful chemical reagent used as a sedative/hypnotic agent for the short-term treatment of insomnia. First developed in 1832, chloral hydrate is the oldest sleep medication still in use today. This medication is also used to calm you just before surgery or other procedures. It works by affecting certain parts of the brain to cause calmness.Studies have shown that when used in pediatric sedation side effects such as hallucination, excessive sleep and seizures were observed. Drowsiness and trouble waking up in the morning, nausea, vomiting, stomach pain, diarrhea, and headache may occur. Stomach problems can be reduced by taking chloral hydrate with a full glass of water. It is sometimes administered to patients being treated with cyclophosphamide and it is known to inhibit some aldehyde dehydrogenases.Besides, Chloral hydrate is a starting point for the synthesis of other organic compounds. It is the starting material for the production of chloral, which is produced by the distillation of a mixture of chloral hydrate and sulfuric acid, which serves as the desiccant.
colourless crystals with a pentrating odour
This chemical is included in Fine Chemicals - Pharmaceutical Intermediates & APIs. See more about what is Chloral hydrate and Chloral hydrate SDS information.
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