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China and the United States are the leading exporters of Trifluoromethanesulfonic anhydride (CAS 358-23-6), together accounting for over 60% of global export value in 2023–2024, while Germany, Japan, and South Korea represent the largest importing markets. Import volumes into the European Union and East Asia have remained relatively stable since 2022, with modest growth observed in semiconductor-producing regions coinciding with upward pressure on Trifluoromethanesulfonic anhydride prices.
Trifluoromethanesulfonic anhydride is a colorless to pale yellow, moisture-sensitive liquid with a pungent odor and high volatility; it has a boiling point of approximately 158–160 °C at atmospheric pressure and solidifies below −15 °C. It is classified as a highly reactive organosulfur compound and a strong electrophilic triflating agent. Primarily used as a key reagent in organic synthesis, it enables efficient introduction of the trifluoromethanesulfonyl (triflyl) group onto nucleophiles such as alcohols, amines, and carbonyl compounds. Its main industrial applications are in the production of pharmaceuticals, agrochemicals, and specialty polymers—particularly where enhanced metabolic stability or acidity modulation is required. It serves as a critical intermediate in synthesizing triflyl-protected functional groups and catalytically active ligands.
Trifluoromethanesulfonic Anhydride is a strong electrophile used in chemical synthesis for introducing the triflyl group.
clear colorless to light brown liquid
This chemical is included in Fine Chemicals. See more about what is Trifluoromethanesulfonic anhydride and Trifluoromethanesulfonic anhydride SDS information.
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